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Melanotan II

Tanning & Pigment

Melanotan II

Also known as MT-2, MT2, Barbie drug

Limited human evidenceNot approvedWADA prohibited

€37

Discussed for: Tanning, libido, appetite suppression.

Sequence: not listed. Modified or non-standard residues are left out on purpose.

Effect strengthHow hard it acts on the body9/10
Proof levelHow well that is shown in humans3/10
Risk levelHow much can go wrong7/10

Editorial 1 to 10 estimates from published research, not measured values. How to read these

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01 / Identity

What it is

Melanotan II is a synthetic cyclic peptide. Main reported uses: tanning, libido, appetite suppression. Current status: not approved anywhere. FDA flagged it as a compounding safety risk (2023).

Molecule type
Synthetic cyclic peptide
How it is taken
Injection (SC), nasal
Other names
MT-2, MT2, Barbie drug

Route only. This library does not publish doses or protocols.

02 / Mechanism

How it is thought to work

Activates melanocortin receptors: darker skin, more libido, less appetite

Mechanisms seen in cells or animals do not always happen the same way in people.

03 / Potential benefits

What people use it for

Tanning, libido, appetite suppression

Limited human evidence

Small or low-quality human data. Most of what is claimed comes from animals, cells or anecdotes.

Listed uses are what people use it for, not proven outcomes.

04 / Known risks

Side effects and risks

Nausea, flushing, new/changing moles, possible melanoma link, spontaneous erections

Risk level 7 of 10

High risk score: serious harms are documented or plausible, and there is little data to rule them out.

Unknown long-term effects count as a risk, not as a clean record.

05 / Regulatory

Regulatory status

Status
Not approved
Details
Not approved anywhere. FDA flagged it as a compounding safety risk (2023)
Sport (WADA)
Yes: S0 (unapproved substance)

Status reflects information up to mid-2026 and changes over time. Check current sources.

06 / Evidence quality

How good is the evidence?

Limited: small human studies

How we grade evidence

07 / Notes and sources

Notes and sources

  • In 2023 the FDA placed it on its list of bulk substances with significant safety concerns for compounding.
  • Products sold online as research peptides are unregulated. Tests of such products often find wrong amounts, impurities or a different compound.
  • Anyone using compounds like this regularly should have medical supervision and bloodwork (for example IGF-1, glucose and HbA1c, hormones, lipids).
  • Source: Peptide Reference Table, an editorial review of published research up to mid-2026. Scores are 1 to 10 editorial estimates, not measured values. Regulatory and WADA status change over time.

Educational information only. Not medical advice. Talk to a qualified healthcare professional before using any compound.

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