Retatrutide ModerateTirzepatide StrongHCG StrongMelanotan II LimitedSemaglutide StrongHexarelin LimitedIGF-1 LR3 None in humansTriptorelin StrongACE-031 ModerateCJC-1295 (with DAC) LimitedTesamorelin StrongLiraglutide StrongMelanotan I StrongPT-141 StrongCagrilintide ModerateMK-677 ModerateKisspeptin-10 ModerateGHRP-2 LimitedGHRP-6 LimitedIGF-1 DES None in humansThymosin Alpha-1 ModerateGonadorelin ModerateCerebrolysin ModerateIpamorelin LimitedMod GRF 1-29 LimitedBPC-157 LimitedTB-500 LimitedDihexa Animal onlyFollistatin 344 Animal onlySS-31 ModerateSermorelin ModerateGHK-Cu ModerateARA-290 ModerateSelank LimitedSemax LimitedLL-37 LimitedUrolithin A ModerateOxytocin ModerateMatrixyl LimitedNAD+ LimitedThymalin LimitedDSIP LimitedEpitalon LimitedMOTS-c Animal onlyKPV Animal onlyFOXO4-DRI Animal onlyMGF / PEG-MGF Animal onlyArgireline LimitedAOD-9604 LimitedPQQ LimitedSpermidine LimitedPinealon Very limitedHumanin Animal only5-Amino-1MQ Animal onlyVilon Very limitedCortagen Very limitedRetatrutide ModerateTirzepatide StrongHCG StrongMelanotan II LimitedSemaglutide StrongHexarelin LimitedIGF-1 LR3 None in humansTriptorelin StrongACE-031 ModerateCJC-1295 (with DAC) LimitedTesamorelin StrongLiraglutide StrongMelanotan I StrongPT-141 StrongCagrilintide ModerateMK-677 ModerateKisspeptin-10 ModerateGHRP-2 LimitedGHRP-6 LimitedIGF-1 DES None in humansThymosin Alpha-1 ModerateGonadorelin ModerateCerebrolysin ModerateIpamorelin LimitedMod GRF 1-29 LimitedBPC-157 LimitedTB-500 LimitedDihexa Animal onlyFollistatin 344 Animal onlySS-31 ModerateSermorelin ModerateGHK-Cu ModerateARA-290 ModerateSelank LimitedSemax LimitedLL-37 LimitedUrolithin A ModerateOxytocin ModerateMatrixyl LimitedNAD+ LimitedThymalin LimitedDSIP LimitedEpitalon LimitedMOTS-c Animal onlyKPV Animal onlyFOXO4-DRI Animal onlyMGF / PEG-MGF Animal onlyArgireline LimitedAOD-9604 LimitedPQQ LimitedSpermidine LimitedPinealon Very limitedHumanin Animal only5-Amino-1MQ Animal onlyVilon Very limitedCortagen Very limited
56
Compounds profiled
8
With strong human evidence
13
With animal data only, or none
17
Approved or prescribed somewhere
37
Prohibited in sport (WADA)
A closer look · BPC-157
From vial to molecule
FIG. 3 · BPC-157, 15 residues
FIG. 3 · BPC-157, 15 residues
01 / 06The vial
01 · THE VIAL
01 · The vial
One vial. Fifteen amino acids.
BPC-157 is a short peptide: a chain of 15 amino acids. Research suppliers ship it as a few milligrams of dry powder sealed in a small glass vial.
02 · The powder
Freeze-dried, not dissolved.
Lyophilised means freeze-dried. The peptide is dissolved in water, frozen, and the ice is then removed under vacuum, leaving a light, dry cake that keeps longer than a liquid would.
03 · Inside
Up close, a chain of letters.
Every molecule in the powder is the same sequence, written in one-letter amino acid codes: GEPPPGKPADDAGLV. The colours mark the chemical class of each residue.
Special (G, P)
Negative
Positive
Hydrophobic
04 · How it is thought to work
How it is thought to work
Proposed mechanism
Promotes new blood vessel growth (angiogenesis) and tissue repair.
Studied for
Tendon, ligament, muscle and gut healing.
Mechanisms seen in cells or animals do not always happen the same way in people.
05 · What the evidence shows
Limited human evidence
Effect strength5/10
Proof level2/10
Risk level5/10
Evidence
Limited: mostly animal; very few human studies.
Approval
Not approved anywhere. FDA flagged it as a compounding safety risk (2023).
06 · What can go wrong
What can go wrong.
Risk level5/10
Unknown long-term; angiogenesis raises theoretical cancer concern.
FIG. 3Every profile is checked against published research before it goes in the library.
Strength ranking
The strongest are often the least tested
Each compound gets three separate scores, because one rating would hide the trade-off. Effect strength is how hard it acts on the body. Proof level is how well that is shown in humans. Risk level is how much can go wrong.
Most "research peptides" sold online have no quality control. Lab tests of these products often find the wrong amount, impurities or a different compound entirely.
02
Animal only means unknown
If a compound has only been tested in animals, its effects and safety in people are unknown. That is not the same as proven safe.
03
Growth signals do not pick targets
Growth-factor peptides such as IGF-1 variants, GH secretagogues, BPC-157 and TB-500 carry a theoretical risk of feeding cancers that already exist.
04
Supervision is not optional
Anyone using these compounds regularly needs medical supervision and bloodwork, such as IGF-1, glucose and HbA1c, hormones and lipids.
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