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Semaglutide

Metabolic & Weight

Semaglutide

Also known as Ozempic, Wegovy, Rybelsus (oral), Sema

Strong human evidenceApproved medicine

Price range: €54 through €100

Discussed for: Weight loss, appetite control, blood sugar.

Sequence: not listed. Modified or non-standard residues are left out on purpose.

Effect strengthHow hard it acts on the body8/10
Proof levelHow well that is shown in humans10/10
Risk levelHow much can go wrong5/10

Editorial 1 to 10 estimates from published research, not measured values. How to read these

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01 / Identity

What it is

Semaglutide is a synthetic GLP-1 analog. Main reported uses: weight loss, appetite control, blood sugar. Current status: FDA/EMA-approved (diabetes, obesity, heart risk).

Molecule type
Synthetic GLP-1 analog
How it is taken
Injection (SC weekly), oral tablet
Other names
Ozempic, Wegovy, Rybelsus (oral), Sema

Route only. This library does not publish doses or protocols.

02 / Mechanism

How it is thought to work

GLP-1 agonist: slows stomach emptying, reduces appetite, raises insulin

03 / Potential benefits

What people use it for

Weight loss, appetite control, blood sugar

Strong human evidence

Large human trials exist. Effects are well described, at least for the approved use.

Listed uses are what people use it for, not proven outcomes.

04 / Known risks

Side effects and risks

Nausea, vomiting, constipation, muscle loss, gallbladder and pancreas issues

Risk level 5 of 10

Moderate risk score: real side effects are known, and long-term safety is not settled.

Unknown long-term effects count as a risk, not as a clean record.

05 / Regulatory

Regulatory status

Status
Approved medicine
Details
FDA/EMA-approved (diabetes, obesity, heart risk)
Sport (WADA)
No

Status reflects information up to mid-2026 and changes over time. Check current sources.

06 / Evidence quality

How good is the evidence?

Strong: large human trials

How we grade evidence

07 / Notes and sources

Notes and sources

  • Anyone using compounds like this regularly should have medical supervision and bloodwork (for example IGF-1, glucose and HbA1c, hormones, lipids).
  • Source: Peptide Reference Table, an editorial review of published research up to mid-2026. Scores are 1 to 10 editorial estimates, not measured values. Regulatory and WADA status change over time.

Educational information only. Not medical advice. Talk to a qualified healthcare professional before using any compound.

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