Educational information only. Not medical advice. Talk to a qualified healthcare professional before using any compound. Disclaimer

Tanning & Pigment

Melanotan I

Also known as Afamelanotide, Scenesse, CUV1647, MT-1

Strong human evidenceApproved medicine

€46

Discussed for: Tanning, sun protection.

Sequence: not listed. Modified or non-standard residues are left out on purpose.

Effect strengthHow hard it acts on the body6/10
Proof levelHow well that is shown in humans8/10
Risk levelHow much can go wrong3/10

Editorial 1 to 10 estimates from published research, not measured values. How to read these

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01 / Identity

What it is

Melanotan I is a synthetic peptide. Main reported uses: tanning, sun protection. Current status: approved (EPP light-sensitivity disorder).

Molecule type
Synthetic peptide
How it is taken
Implant under skin
Other names
Afamelanotide, Scenesse, CUV1647, MT-1

Route only. This library does not publish doses or protocols.

02 / Mechanism

How it is thought to work

Melanocortin-1 agonist that increases skin pigment

03 / Potential benefits

What people use it for

Tanning, sun protection

Strong human evidence

Large human trials exist. Effects are well described, at least for the approved use.

Listed uses are what people use it for, not proven outcomes.

04 / Known risks

Side effects and risks

Nausea, headache, skin darkening, mole changes

Risk level 3 of 10

Lower risk score: reported side effects are mostly mild. Low risk is not no risk, especially for unregulated products.

Unknown long-term effects count as a risk, not as a clean record.

05 / Regulatory

Regulatory status

Status
Approved medicine
Details
Approved (EPP light-sensitivity disorder)
Sport (WADA)
Not listed

Status reflects information up to mid-2026 and changes over time. Check current sources.

06 / Evidence quality

How good is the evidence?

Strong for EPP

How we grade evidence

07 / Notes and sources

Notes and sources

  • Anyone using compounds like this regularly should have medical supervision and bloodwork (for example IGF-1, glucose and HbA1c, hormones, lipids).
  • Source: Peptide Reference Table, an editorial review of published research up to mid-2026. Scores are 1 to 10 editorial estimates, not measured values. Regulatory and WADA status change over time.

Educational information only. Not medical advice. Talk to a qualified healthcare professional before using any compound.