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PT-141

Libido & Bonding

PT-141

Also known as Bremelanotide, Vyleesi

Strong human evidenceApproved medicine

€44

Discussed for: Arousal and libido (men and women).

Sequence: not listed. Modified or non-standard residues are left out on purpose.

Effect strengthHow hard it acts on the body6/10
Proof levelHow well that is shown in humans8/10
Risk levelHow much can go wrong4/10

Editorial 1 to 10 estimates from published research, not measured values. How to read these

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01 / Identity

What it is

PT-141 is a synthetic cyclic peptide. Main reported uses: arousal and libido (men and women). Current status: FDA-approved (women, low desire); men off-label.

Molecule type
Synthetic cyclic peptide
How it is taken
Injection (SC), nasal (grey market)
Other names
Bremelanotide, Vyleesi

Route only. This library does not publish doses or protocols.

02 / Mechanism

How it is thought to work

Activates brain melanocortin receptors, raising sexual desire

03 / Potential benefits

What people use it for

Arousal and libido (men and women)

Strong human evidence

Large human trials exist. Effects are well described, at least for the approved use.

Listed uses are what people use it for, not proven outcomes.

04 / Known risks

Side effects and risks

Nausea, flushing, raised blood pressure, skin darkening

Risk level 4 of 10

Moderate risk score: real side effects are known, and long-term safety is not settled.

Unknown long-term effects count as a risk, not as a clean record.

05 / Regulatory

Regulatory status

Status
Approved medicine
Details
FDA-approved (women, low desire); men off-label
Sport (WADA)
Not listed

Status reflects information up to mid-2026 and changes over time. Check current sources.

06 / Evidence quality

How good is the evidence?

Strong (women)

How we grade evidence

07 / Notes and sources

Notes and sources

  • Anyone using compounds like this regularly should have medical supervision and bloodwork (for example IGF-1, glucose and HbA1c, hormones, lipids).
  • Source: Peptide Reference Table, an editorial review of published research up to mid-2026. Scores are 1 to 10 editorial estimates, not measured values. Regulatory and WADA status change over time.

Educational information only. Not medical advice. Talk to a qualified healthcare professional before using any compound.

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