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DSIP

Sleep

DSIP

Also known as Delta Sleep-Inducing Peptide, Emideltide

Limited human evidenceNot approvedWADA prohibited

Price range: €30 through €48

Discussed for: Deeper sleep, stress.

FIG. 2 ยท Amino-acid sequence of DSIP (9 residues)
  1. W
  2. A
  3. G
  4. G
  5. D
  6. A
  7. S
  8. G
  9. E
  • Hydrophobic
  • Polar
  • Positive charge
  • Negative charge
  • Glycine / proline
Effect strengthHow hard it acts on the body3/10
Proof levelHow well that is shown in humans3/10
Risk levelHow much can go wrong2/10

Editorial 1 to 10 estimates from published research, not measured values. How to read these

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01 / Identity

What it is

DSIP is a natural nonapeptide (9 aa). Main reported uses: deeper sleep, stress. Current status: not approved anywhere. FDA flagged it as a compounding safety risk (2023).

Molecule type
Natural nonapeptide (9 aa)
How it is taken
Injection (SC)
Other names
Delta Sleep-Inducing Peptide, Emideltide

Route only. This library does not publish doses or protocols.

02 / Mechanism

How it is thought to work

Promotes delta (deep) sleep phases; exact mechanism unclear

Mechanisms seen in cells or animals do not always happen the same way in people.

03 / Potential benefits

What people use it for

Deeper sleep, stress

Limited human evidence

Small or low-quality human data. Most of what is claimed comes from animals, cells or anecdotes.

Listed uses are what people use it for, not proven outcomes.

04 / Known risks

Side effects and risks

Headache, grogginess

Risk level 2 of 10

Lower risk score: reported side effects are mostly mild. Low risk is not no risk, especially for unregulated products.

Unknown long-term effects count as a risk, not as a clean record.

05 / Regulatory

Regulatory status

Status
Not approved
Details
Not approved anywhere. FDA flagged it as a compounding safety risk (2023)
Sport (WADA)
Yes: S0 (unapproved substance)

Status reflects information up to mid-2026 and changes over time. Check current sources.

06 / Evidence quality

How good is the evidence?

Limited: small human studies, mixed

How we grade evidence

07 / Notes and sources

Notes and sources

  • In 2023 the FDA placed it on its list of bulk substances with significant safety concerns for compounding.
  • Products sold online as research peptides are unregulated. Tests of such products often find wrong amounts, impurities or a different compound.
  • Anyone using compounds like this regularly should have medical supervision and bloodwork (for example IGF-1, glucose and HbA1c, hormones, lipids).
  • Source: Peptide Reference Table, an editorial review of published research up to mid-2026. Scores are 1 to 10 editorial estimates, not measured values. Regulatory and WADA status change over time.

Educational information only. Not medical advice. Talk to a qualified healthcare professional before using any compound.

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