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ACE-031

Growth Hormone & Muscle

ACE-031

Also known as Ramatercept, ActRIIB-Fc

Moderate human evidenceNot approvedWADA prohibited

€145

Discussed for: Bigger muscles.

Sequence: not listed. Modified or non-standard residues are left out on purpose.

Effect strengthHow hard it acts on the body7/10
Proof levelHow well that is shown in humans5/10
Risk levelHow much can go wrong9/10

Editorial 1 to 10 estimates from published research, not measured values. How to read these

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01 / Identity

What it is

ACE-031 is a fusion protein. Main reported uses: bigger muscles. Current status: not approved, human trials stopped.

Molecule type
Fusion protein
How it is taken
Injection (SC)
Other names
Ramatercept, ActRIIB-Fc

Route only. This library does not publish doses or protocols.

02 / Mechanism

How it is thought to work

Decoy receptor that blocks myostatin and related signals

03 / Potential benefits

What people use it for

Bigger muscles

Moderate human evidence

Some human trials exist, but they are smaller, shorter or mixed.

Listed uses are what people use it for, not proven outcomes.

04 / Known risks

Side effects and risks

Nosebleeds, gum bleeding, dilated blood vessels

Risk level 9 of 10

High risk score: serious harms are documented or plausible, and there is little data to rule them out.

Unknown long-term effects count as a risk, not as a clean record.

05 / Regulatory

Regulatory status

Status
Not approved
Details
Not approved, human trials stopped
Sport (WADA)
Yes: S4 (myostatin inhibitors)

Status reflects information up to mid-2026 and changes over time. Check current sources.

06 / Evidence quality

How good is the evidence?

Moderate: Phase 2 stopped for safety

How we grade evidence

07 / Notes and sources

Notes and sources

  • Growth-factor peptides carry a theoretical risk of feeding existing cancers.
  • Products sold online as research peptides are unregulated. Tests of such products often find wrong amounts, impurities or a different compound.
  • Anyone using compounds like this regularly should have medical supervision and bloodwork (for example IGF-1, glucose and HbA1c, hormones, lipids).
  • Source: Peptide Reference Table, an editorial review of published research up to mid-2026. Scores are 1 to 10 editorial estimates, not measured values. Regulatory and WADA status change over time.

Educational information only. Not medical advice. Talk to a qualified healthcare professional before using any compound.

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